Because Retin-A can cause skin to become sensitive, we do not recommend you use the Microfine Face Scrub while using it. Exfoliating already sensitive skin can result in increased burning, itching, peeling, redness, and stinging. You should check with a dermatologist before using any products to see how they will fit in with your present treatment. A better bet may be for you to use a gentle face wash like Daily Face Wash and an oil-free moisturizer like Advanced Face Lotion to keep skin well-hydrated.